Facilitates Bioprocess Scale-Up and Cultivation

The Applikon BioPilot from Getinge is a versatile stainless steel bioreactor designed for biopharmaceutical and vaccine manufacturing. This multi-use pilot plant bioreactor simplifies the transfer from lab scale to production with its modular design and Sterilize-in-Place capability. It’s optimized for cultivating microbial and cell cultures, producing vital therapies like monoclonal antibodies and mRNA vaccines. With working volumes ranging from 20 to 200 liters, the BioPilot excels in scale-up studies, process optimization, and small-scale production. It features PLC automation for precise control and is constructed from pharma-grade 316L stainless steel, ensuring compliance with cGMP standards. The integrated magnetic agitator system and hygienic design minimize contamination risk, while its robust configuration supports both batch and continuous operations.

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Cultivates and Ferments Microbial and Cell Cultures

The Applikon BioProduction system from Getinge is a stainless steel bioreactor designed to meet the stringent demands of pharmaceutical and biopharmaceutical manufacturing. This system is engineered for precise control over cultivation and fermentation processes, making it ideal for producing vaccines, monoclonal antibodies, and various biological drugs. It operates using a fully automated Cultivation, Fermentation, and Sterilization process, which includes advanced temperature, pH, and DO2 control systems for optimal microbial and cell culture growth.

Applications span across pharmaceutical and biotech industries, where it supports the production of insulin, onco-therapeutic vaccines, and CAR-T cell therapies. Offering capacities for both pilot and full-scale production, it can handle volumes up to 5,000 liters. The system integrates seamlessly into existing lines with PLC control options for Siemens and Allen Bradley, providing flexibility in automation and remote monitoring via a DCS.

Energy-efficient design is achieved through its magnetically coupled agitation system, minimizing contamination risks while enhancing mixing efficiency. The bioreactors are fabricated with pharma-grade 316L stainless steel, featuring a surface finish of Ra

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Cultivates and Processes Microbial and Cell Cultures

The Applikon BioBench from Getinge is a versatile stainless steel bench-scale bioreactor designed for precision in biopharmaceutical applications. Ideal for microbial and cell cultures, this equipment mimics commercial-scale processes in a compact form, maintaining essential geometric ratios. It supports operations like cultivation, sampling, draining, sterilization, heating, cooling, and mixing. With capacities ranging from 15 to 30 liters, it caters to scale-up studies and small-scale production of monoclonal antibodies, vaccines, and recombinant proteins. Its Sterilizable-in-Place feature minimizes contamination risks, while the open frame construction ensures easy maintenance. The bioreactor is built with durable 316L stainless steel, offering resistance to biofilms and ensuring compliance with cGMP standards. Customization options and engineering support are available to meet specific process demands.

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Weighs and Loads Liquid Dairy Products

The Milk Reception Unit from Uzermak is engineered to enhance your dairy production line through precise load cell measurement and seamless liquid handling. Constructed from durable AISI304 stainless steel, it withstands rigorous processing environments. This unit accommodates customizable capacities, ensuring it meets your specific operational needs. It efficiently weighs and loads a range of dairy products including milk, cheese, yogurt, and more, supporting diverse applications from milk processing to dairy product formulation. Automated weight calculation is facilitated through its integrated load cell system, offering reliability and accuracy. Ideal for integration into milk receiving and pre-processing departments, this unit streamlines operations in food, dairy, and beverage industries. Its vertical or cylindrical design and perforated internal layer provide robust structural integrity, enhancing its adaptability and ease of maintenance across varied environments.

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Stores and Mixes Liquid Dairy Products

The Milk Storage and Mixing Tank from Uzermak is engineered to meet the diverse needs of dairy producers, food processing companies, and beverage manufacturers. It stands out for its versatility, capable of storing, mixing, and ventilating liquid products such as milk, cream, yogurt, and liquid cheese. Utilizing AISI 304 or AISI 216 quality stainless steel, the tank offers excellent corrosion resistance, making it ideal for food-grade applications.

Its capacity is customizable to fit your specific production requirements, with both cylindrical and vertical configurations available. The tank supports batch and manual operations, while its integrated mixer ensures homogeneity in liquid formulations. For energy efficiency, optional insulation minimizes heat loss during storage.

The system is compatible with CIP (Clean-in-Place) cleaning, ensuring hygiene standards and simplifying maintenance. Moreover, Uzermak offers comprehensive engineering support for tailored product inlet and outlet dimensions, as well as options for isolated or non-isolated configurations, to seamlessly integrate into your existing production line.

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