Refines wet milling with clean and sterile technology

The DYNO^®-MILL MULTI LAB CIP/SIP from WAB-GROUP^® is a specially designed agitator wet mill for sterile research and development, pilot, and production operations in the pharma industry. It can process low to high-viscous products with batch sizes starting from 500 ml. What is more, it comes with easily interchangeable grinding chambers from 0.3 l to 1.4 l. It can accommodate both, WAB KD agitator discs as well as the DYNO^®-ACCELERATOR. The use of agitating small beads in wet milling efficiently grinds suspended particles to the low micrometer or even nanometer range, maintaining a narrow particle size distribution.

Cleaning in Place (CIP) ensures there is no direct contact between the plant operator and active pharmaceutical ingredients. Steam sterilization up to 135°C ensures plant sterility, guaranteeing a germ-free production of tablets, capsules, injectables, and vaccines.

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Blends and Uniformly Mixes Powders and Granules

The Uni-Blend bin blender from Hanningfield is engineered to precisely mix and blend powders and granules across diverse industries such as pharmaceuticals and chemicals. Utilizing a gentle tumbling action, it ensures uniform batch consistency ideal for tablet formulations and dietary supplements. Designed for flexibility, it accommodates container sizes up to 2000 liters and supports efficient batch processing without the need for washdown, thanks to its ‘Blend-in-the-Bin’ capability. This unit offers integrated control systems conforming to 21 CFR Part 11 for compliance in regulated environments. Fabricated with stainless steel, the Uni-Blend withstands corrosive substances, making it suitable for sanitary applications. Customizable for specific needs, options include various mounting configurations such as stand-alone, through-the-wall, and post hoist. Supporting full validation with procedural documentation and 3.1 mill certificates, this blender is engineered to meet GMP standards, simplifying cleaning and maintenance through offline charging and discharging, thereby optimizing operational efficiency.

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Shreds and Reduces Size of Bulk Materials

The Hanningfield Pharmaceutical Shredder is a purpose-built solution for achieving efficient pre-milling size reduction of bulk materials such as pharmaceutical powders and nutraceutical granules. This shredder stands out with its compact design, suitable for inline integration within continuous processing operations. The unit operates by rapidly shredding and reducing the size of agglomerated powders and granules, using rotational speeds of 1,000-2,000 RPM for effective grinding.

Ideal for applications in pharmaceuticals, nutraceuticals, fine chemicals, and cannabis industries, it supports the production of tablets, capsules, dietary supplements, and herbal extracts by preparing materials for subsequent milling processes. Its high throughput capacity ensures maximum productivity, seamlessly integrating with upstream and downstream equipment via tri-clover connections.

Constructed with FDA-compliant 316L stainless steel contact parts for superior corrosion resistance, the shredder complies with GMP standards. The equipment offers a clean, GMP design with easy maintenance and is customizable with various sizes to meet specific throughput requirements. Hanningfield provides full engineering support, ensuring each machine aligns with your operational needs, complete with detailed validation documentation and certifications for compliance.

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Lifts and Maneuvers Bulk Containers and Materials

The Hanningfield Uni-Hoist series offers fully customizable lift systems designed for industrial material handling across diverse sectors, including pharmaceutical, food, and chemical industries. Engineered to streamline processes, these hoists allow you to raise, lower, rotate, and invert Intermediate Bulk Containers (IBCs), drums, bins, and more with ease. Using a lead-screw or chain lifting mechanism, they ensure safe, repeatable operations in hygienic conditions, reducing energy consumption with manual, electric, and pneumatic models available.

Uni-Hoist systems cater to a variety of applications, from handling pharmaceutical powders to chemical reagents and cannabis products. The systems are designed to integrate seamlessly with your processing line, enabling precise maneuvering and efficient docking of materials, which optimizes workflow and enhances operator safety by eliminating the need for manual lifting.

Available in stainless steel construction suited for GMP environments, these hoists come with options for ATEX compliance, ensuring safe use in explosive atmospheres when required. The Uni-Hoist’s modular design features various attachments like lifting forks and clamp arms, making it adaptable to specific operational needs. The systems support capacities ranging from light-duty (250 kgs) to heavy-duty (2,000 kgs), compliant with industry standards for material handling. With thorough validation documentation available, these hoists represent a reliable, efficient solution for lifting and handling requirements.

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Mixes and Blends Powders and Granules

The Drum Tumblers from Hanningfield are designed to efficiently mix and blend powders, granules, and solids for industries such as pharmaceutical, food and beverage, chemical, and nutraceutical. This versatile equipment supports batch, stand-alone, and portable operations, with models capable of handling containers up to 200 liters and a safe working load of 200 kilograms. Employing variable RPM for tailored operation, it ensures uniform batch processing, critical for consistent end-product quality across pharmaceuticals, nutritional supplements, and more. Constructed with 316L stainless steel, the drum tumblers are compliant with GMP standards and can be equipped with controls meeting 21 CFR Part 11 for data recording and traceability. Transitioning between batches is efficient with minimal downtime, and an optional portable loading cart enhances operational flexibility. Full validation documentation and engineering support are available, making it adaptable to your production line needs.

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Automates and Optimizes Drum Tipping

The Drum Tippers by Hanningfield provide an automated solution for industrial material handling, offering a significant improvement over manual processes. Designed to automate and optimize drum tipping and positioning, these tippers are ideal for industries including pharmaceuticals, food and beverage, nuclear, chemical, and cannabis. Capable of handling solids, powders, and granules, they ensure a seamless fit into your existing production line with options for both manual and automated operations.

Constructed from durable stainless steel, Hanningfield Drum Tippers conform to GMP requirements, making them suitable for high integrity applications such as docking to inflatable seals on isolators. Their design supports multiple tipping heights for process flexibility and includes ATEX (ex-proof) versions for operations in potentially explosive environments.

These drum tippers offer robust integration possibilities, whether configured as a fixed base unit or a mobile trolley, and can accommodate a variety of drum sizes with optional outlet chutes or valve systems. Comprehensive documentation, compliance with standards like EN10204, and support for validation are provided to ensure smooth implementation and adherence to industry regulations. Tailored engineering support is available to match specific needs, including customization of tipping criteria and configuration.

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Controls Dust and Empties Bags Efficiently

The Sack Tip Station by Hanningfield Process Systems is engineered for precise and efficient powder handling across various industries, including pharmaceuticals, food and beverage, chemicals, and nutraceuticals. Its core innovation lies in the ability to integrate seamlessly into existing production lines, facilitating manual or continuous operations. This station addresses dust control challenges by incorporating a dust extraction system that safeguards the operator and environment. It is constructed from durable 316L stainless steel for high corrosion resistance and features FDA-compliant seals for stringent hygiene standards. Typically used to empty bags efficiently, it can integrate with downstream vacuum conveyors or alternative transfer methods, optimizing workflow. The Sack Tip Station supports customization options to perfectly align with specific application needs and can include validation documentation for regulatory compliance.

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Regulates and Controls Powder Flow

The Powder Flow Control System from Hanningfield is designed for the precise regulation of powder transfer in pharmaceutical, nutraceutical, and food processing environments. Featuring a robust rotary valve mechanism, it enables controlled dosing and efficient discharge regulation, essential for operations needing uninterrupted powder flow. This system is specially tailored for applications such as tablet and capsule production, dietary supplements, and beverage flavorings, ensuring minimal waste and optimal product integrity. Constructed from 316L stainless steel and equipped with FDA-compliant seals, it assures compliance with stringent industry standards for hygiene and corrosion resistance. Integration is seamless with existing machinery, utilizing PLC controls for continuous and automated processing, and features like level monitoring and sampling ports to prevent overflow and ensure quality assurance. The unit’s tri-clover clamps facilitate easy disassembly, promoting quick cleaning and maintenance, crucial for minimizing downtime and upholding cleanliness. Adaptations, such as varying flange types, permit compatibility with diverse production settings, backed by engineering support for specialized customization requirements.

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Processes and Reduces Particle Size in Powders

The Uni-Mill M20-B from Hanningfield is an engineered-to-order conical mill designed for high-capacity production. Utilizing an over-driven milling system, it processes and reduces particle sizes efficiently with a throughput of up to 1,800 kg/hr. Featuring a 203mm screen and 4.0kW motor set at 1480RPM, the M20-B offers variable speed for optimized control. It adeptly handles powders and granules in industries such as pharmaceuticals, food, chemicals, and nuclear, producing tablets, capsules, and various powdered products. Constructed from 316L stainless steel, it ensures durability and resistance to corrosion, suitable for GMP and FDA-compliant operations. Equipped with customizable tooling and mounting options, it seamlessly integrates into your production line, tailored to meet specific process requirements.

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Reduces Particle Size through Shearing and Compression

The Uni-Mill B-Series from Hanningfield offers a robust solution for precise particle reduction through its over-driven conical milling design. Using a belt-driven impeller, the Uni-Mill compresses and shears material to achieve efficient size reduction with minimal heat generation, making it ideal for processing pharmaceuticals, nutraceuticals, and chemicals. With models ranging from the M10-B to the M60-B, it caters to varying throughput needs, from low to high capacity, handling up to 7200 kg/hr. The stainless steel construction ensures compliance with FDA standards, while ATEX options offer enhanced safety for explosive environments. Its adaptable design supports both wet and dry milling, integrating seamlessly into continuous, automated production lines. Customizable features, including screen variability and inlet and outlet configurations, offer further flexibility, supported by comprehensive validation documentation (FS/DS, FAT, SAT, IQ/OQ) and CIP systems for easy maintenance.

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