Refines wet milling with clean and sterile technology

The DYNO^®-MILL MULTI LAB CIP/SIP from WAB-GROUP^® is a specially designed agitator wet mill for sterile research and development, pilot, and production operations in the pharma industry. It can process low to high-viscous products with batch sizes starting from 500 ml. What is more, it comes with easily interchangeable grinding chambers from 0.3 l to 1.4 l. It can accommodate both, WAB KD agitator discs as well as the DYNO^®-ACCELERATOR. The use of agitating small beads in wet milling efficiently grinds suspended particles to the low micrometer or even nanometer range, maintaining a narrow particle size distribution.

Cleaning in Place (CIP) ensures there is no direct contact between the plant operator and active pharmaceutical ingredients. Steam sterilization up to 135°C ensures plant sterility, guaranteeing a germ-free production of tablets, capsules, injectables, and vaccines.

The post Agitátoros gyöngymalom API számára appeared first on Holimex Hungary.

Achieves perfect homogenization of APIs with three-dimensional mixing

TURBULA^®, a 3D shaker mixer from WAB-GROUP^®, is designed for uniformly mixing powdery substances with diverse particle sizes and specific weights. It excels in handling both wet and dry components, like powder inhalers or API.  Based on the Schatz geometric theory, its distinctive three-dimensional motion incorporates rotation, translation, and inversion. It facilitates a dynamic and harmonious mixing of the API with the carrier material. This constant, rhythmic pulsing motion of the shaker container ensures exposure to a vibrant, homogeneous mixing. Available in a range of configurations to accommodate container volumes spanning from 0.1 to 55 liters, the 3D shaker mixer proves its versatility across various pharma industries, R&D labs, as well as pharma production plants.

The post 3D porkeverő gyógyszerhatóanyagokhoz appeared first on Holimex Hungary.

Employs ultra-fine grinding for cell disruption and extraction of ingredients

DYNO^®-MILL MULTI LAB (ML) from WAB-GROUP^® is an adaptable laboratory agitator bead mill, well-suited for small-scale productions and R&D in biotechnology. Suitable in continuous and discontinuous operations, the bead mill specifically designed for smaller applications can utilize ultra-fine grinding beads as small as 0.1mm. It has adjustable grinding chamber sizes, material selection, and adaptable grinding technology. It incorporates two grinding principles in one mill: the DYNO^® agitator disc and the patented DYNO^®-ACCELERATOR.

Discontinuous operation utilizes grinding vessels of 0.15 l and 0.3 l to handle low-viscosity suspensions. The batches range from 85 ml to 170 ml. Continuous operation is suitable for processing highly fluid to viscous, pumpable products.  It employs grinding containers of 0.15, 0.3, 0.6, and 1.4 l to process batch sizes exceeding 500 ml. Using superior ceramic components such as SiC and ZrO₂ ensures no metal contamination and an extended service life.

The post Rugalmas laboratóriumi gyöngymalom vakcinákhoz appeared first on Holimex Hungary.

Transfers and Loads Capsules Efficiently

The Hanningfield CapsuJet Capsule Transfer Systems, including the C20 and FCC models, revolutionize capsule handling for pharmaceutical manufacturers and nutraceutical companies. Designed to enhance the efficiency of pill production lines, these systems excel in automating the loading and unloading processes for both empty and filled capsules.

The CapsuJet C20 efficiently transfers up to 300,000 empty capsules per hour from ground-level hoppers into filling machines, while the CapsuJet FCC manages filled capsules, conveying up to 200,000 per hour to downstream processes. Both models utilize a gentle conveyance method to minimize capsule damage, making them ideal for a wide array of capsule types including gelatin, vegetarian, and CBD capsules.

Constructed with 316L stainless steel contact parts and FDA-compliant seals, these systems offer robust durability and compliance with stringent pharmaceutical standards. The optional level control feature facilitates automated loading, reducing manual intervention and ensuring consistency during high-speed operations. Customizable hoppers accommodate various capsule sizes, further enhancing flexibility.

Integration into existing production lines is seamless, supported by full validation documentation and customization options to meet specific operational demands. Whether you’re in the pharmaceutical, food and beverage, or chemical industry, Hanningfield’s CapsuJet systems provide reliable, high-performance solutions for your capsule handling needs.

The post Kapszulaszállítók a kapszulák kíméletes szállítására appeared first on Holimex Hungary.

Blends and Uniformly Mixes Powders and Granules

The Uni-Blend bin blender from Hanningfield is engineered to precisely mix and blend powders and granules across diverse industries such as pharmaceuticals and chemicals. Utilizing a gentle tumbling action, it ensures uniform batch consistency ideal for tablet formulations and dietary supplements. Designed for flexibility, it accommodates container sizes up to 2000 liters and supports efficient batch processing without the need for washdown, thanks to its ‘Blend-in-the-Bin’ capability. This unit offers integrated control systems conforming to 21 CFR Part 11 for compliance in regulated environments. Fabricated with stainless steel, the Uni-Blend withstands corrosive substances, making it suitable for sanitary applications. Customizable for specific needs, options include various mounting configurations such as stand-alone, through-the-wall, and post hoist. Supporting full validation with procedural documentation and 3.1 mill certificates, this blender is engineered to meet GMP standards, simplifying cleaning and maintenance through offline charging and discharging, thereby optimizing operational efficiency.

The post Ibc tumbler egyenletes tételes keveréshez appeared first on Holimex Hungary.

Shreds and Reduces Size of Bulk Materials

The Hanningfield Pharmaceutical Shredder is a purpose-built solution for achieving efficient pre-milling size reduction of bulk materials such as pharmaceutical powders and nutraceutical granules. This shredder stands out with its compact design, suitable for inline integration within continuous processing operations. The unit operates by rapidly shredding and reducing the size of agglomerated powders and granules, using rotational speeds of 1,000-2,000 RPM for effective grinding.

Ideal for applications in pharmaceuticals, nutraceuticals, fine chemicals, and cannabis industries, it supports the production of tablets, capsules, dietary supplements, and herbal extracts by preparing materials for subsequent milling processes. Its high throughput capacity ensures maximum productivity, seamlessly integrating with upstream and downstream equipment via tri-clover connections.

Constructed with FDA-compliant 316L stainless steel contact parts for superior corrosion resistance, the shredder complies with GMP standards. The equipment offers a clean, GMP design with easy maintenance and is customizable with various sizes to meet specific throughput requirements. Hanningfield provides full engineering support, ensuring each machine aligns with your operational needs, complete with detailed validation documentation and certifications for compliance.

The post Gyógyszeripari méretcsökkentő aprító appeared first on Holimex Hungary.

Lifts and Maneuvers Bulk Containers and Materials

The Hanningfield Uni-Hoist series offers fully customizable lift systems designed for industrial material handling across diverse sectors, including pharmaceutical, food, and chemical industries. Engineered to streamline processes, these hoists allow you to raise, lower, rotate, and invert Intermediate Bulk Containers (IBCs), drums, bins, and more with ease. Using a lead-screw or chain lifting mechanism, they ensure safe, repeatable operations in hygienic conditions, reducing energy consumption with manual, electric, and pneumatic models available.

Uni-Hoist systems cater to a variety of applications, from handling pharmaceutical powders to chemical reagents and cannabis products. The systems are designed to integrate seamlessly with your processing line, enabling precise maneuvering and efficient docking of materials, which optimizes workflow and enhances operator safety by eliminating the need for manual lifting.

Available in stainless steel construction suited for GMP environments, these hoists come with options for ATEX compliance, ensuring safe use in explosive atmospheres when required. The Uni-Hoist’s modular design features various attachments like lifting forks and clamp arms, making it adaptable to specific operational needs. The systems support capacities ranging from light-duty (250 kgs) to heavy-duty (2,000 kgs), compliant with industry standards for material handling. With thorough validation documentation available, these hoists represent a reliable, efficient solution for lifting and handling requirements.

The post Ipari konténer emelőrendszer appeared first on Holimex Hungary.

Mixes and Blends Powders and Granules

The Drum Tumblers from Hanningfield are designed to efficiently mix and blend powders, granules, and solids for industries such as pharmaceutical, food and beverage, chemical, and nutraceutical. This versatile equipment supports batch, stand-alone, and portable operations, with models capable of handling containers up to 200 liters and a safe working load of 200 kilograms. Employing variable RPM for tailored operation, it ensures uniform batch processing, critical for consistent end-product quality across pharmaceuticals, nutritional supplements, and more. Constructed with 316L stainless steel, the drum tumblers are compliant with GMP standards and can be equipped with controls meeting 21 CFR Part 11 for data recording and traceability. Transitioning between batches is efficient with minimal downtime, and an optional portable loading cart enhances operational flexibility. Full validation documentation and engineering support are available, making it adaptable to your production line needs.

The post Ipari dobtörők egyenletes tételes feldolgozáshoz appeared first on Holimex Hungary.

Automates and Optimizes Drum Tipping

The Drum Tippers by Hanningfield provide an automated solution for industrial material handling, offering a significant improvement over manual processes. Designed to automate and optimize drum tipping and positioning, these tippers are ideal for industries including pharmaceuticals, food and beverage, nuclear, chemical, and cannabis. Capable of handling solids, powders, and granules, they ensure a seamless fit into your existing production line with options for both manual and automated operations.

Constructed from durable stainless steel, Hanningfield Drum Tippers conform to GMP requirements, making them suitable for high integrity applications such as docking to inflatable seals on isolators. Their design supports multiple tipping heights for process flexibility and includes ATEX (ex-proof) versions for operations in potentially explosive environments.

These drum tippers offer robust integration possibilities, whether configured as a fixed base unit or a mobile trolley, and can accommodate a variety of drum sizes with optional outlet chutes or valve systems. Comprehensive documentation, compliance with standards like EN10204, and support for validation are provided to ensure smooth implementation and adherence to industry regulations. Tailored engineering support is available to match specific needs, including customization of tipping criteria and configuration.

The post Hordóbillenők a pontos és biztonságos hordókezeléshez appeared first on Holimex Hungary.